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Akt substrate of 160 kDa (AS160) is a Rab GTPase-activating protein (RabGAP) with an extensive distribution on tissues, which participates in the membrane trafficking when Akt phosphorylates it via inhibiting the activity of the Rab-GTP enzyme and triggering the migration of the GLUT-4 storage vesicles (GSVs), completing the final translocation of GLUT-4 (7)

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All PCR reactions were coupled to melting-curve analysis to confirm the amplification specificity

Narahara H et al

Suppliers who cannot or do not provide these documents for both compounds in this stack create unnecessary uncertainty about whether any protocol results are reflecting the compounds true pharmacological properties