However, continuing treatment beyond one year is typically safe and can further assist in weight maintenance
The body can no longer rely on the drug to reduce appetite, slowing the metabolism and causing the hunger hormone to kick back in, causing weight regain
The FDA grants separate approvals for separate indications, which allows Novo Nordisk to market the same molecule under different names
What makes it stand out is that it targets three hormone pathways simultaneously: GLP-1, GIP and glucagon, [which are] involved in hunger, fullness, blood sugar [regulation] and metabolism
The catch is that the effect requires consistent, high-dose exposure, fades when treatment stops, and works very unevenly between individuals