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10.1007/s00438-004-1006-8 Mol

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This pathway consists of ascorbate, glutathione, and four enzymes, namely ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, and GR, which can contribute to the effective scavenging of ROS

Studies with NR supplementation in PD or HF patients have provided indications of impacting mitochondrial function in peripheral tissues, although evidence for impacting mitochondria in the primary target tissues was not reported 318,319

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