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But if glycaemic benefit really does plateau around 9 mg while weight loss and adverse events keep climbing, then dose selection in the patient whose primary problem is glycaemic becomes a real clinical decision rather than a titrate-to-max reflex
Exendin-4 also rescues the cytokine-induced reduction of electron transport chain proteins of mitochondria and leads to decrease oxidative stress and alleviate apoptosis 11
By increasing dopamine and norepinephrine levels it helps reduce appetite, control cravings, and improve energy
Semaglutide has a dose-dependent effect