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The safety of Glutathione Therapy, like any therapeutic intervention, is of paramount importance

Multiple clinical trials show improvements in wrinkle depth, skin elasticity, and UV-induced damage after 612 weeks of supplementation (Tominaga et al., 2012, Acta Biochimica Polonica )

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That said, "no serious toxicity in animal models" is not the same as "proven safe in humans long-term," and anyone with a personal or family history of cancer should treat the angiogenic mechanism above as a genuine reason to talk to a qualified clinician before starting