steer study semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial Adith Arun on X: "Three

This is one of the main arguments for the 4-8 week off protocol, not the indefinite supply

The long term numbers look very encouraging

If you lose calf muscle, the pump gets weaker, and blood can pool more easily in your legs, worsening vein disease and venous insufficiency

In another study, Mansour et al

Contact your healthcare provider within 24 hours for: New or worsening abdominal pain that is moderate in severity and localized to the right upper abdomen Recurrent episodes of pain after eating, particularly fatty meals Persistent nausea or vomiting that is worsening rather than improving over time Any abdominal symptoms that concern you or differ from your usual experience with the medication Routine follow-up appointments should include discussion of any gastrointestinal symptoms, weight loss patterns, and overall tolerance of the medication