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Helpware CXs 2.8% monthly attrition rate compares favorably with the 6 to 8% industry average, meaning lower hidden retraining costs over a multi-year engagement

(1) J Ishida, M Saitoh, N Ebner, J Springer, et al (2020) Growth hormone secretagogues: history, mechanism of action, and clinical development JCSM Communications, Volume 3, Issue 1, January/June 2020, Pages 25-37

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The primary mechanisms of action include: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood glucose levels without causing hypoglycaemia when used alone [17] [18] Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production Slowing gastric emptying , which prolongs satiety and reduces postprandial glucose excursions Reducing appetite through central nervous system pathways, particularly in the hypothalamus, leading to decreased caloric intake and weight loss It's important to note that while GLP-1 receptor agonists have a low risk of hypoglycaemia when used alone, this risk increases when combined with insulin or sulfonylureas

One study reported that somatostatin does not suppress insulin secretion by acting on the central nervous system but acts peripherally on islet beta-cells