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Administration of an acylated GLP-1 and GIP preparation provides added beneficial glucose-lowering and insulinotropic actions over single incretins in mice with Type 2 diabetes and obesity
This dynamic duo is the special sauce that made Neededs Stress Support supplement an easy pick as our best ashwagandha supplement for stress
Contact your GP or diabetes specialist if you experience: Unexplained bone pain or persistent musculoskeletal discomfort Fractures from minor trauma (fragility fractures), which may indicate underlying bone weakness Significant unintentional weight loss of 5-10% over 3-6 months Difficulty maintaining adequate nutrition due to gastrointestinal side effects New or worsening symptoms suggesting calcium or vitamin D deficiency (muscle cramps, weakness, fatigue) Proactive discussion is particularly important if you: Are postmenopausal or over 65 years of age Have a personal or family history of osteoporosis or fragility fractures Take medications that affect bone health (corticosteroids, aromatase inhibitors, pioglitazone) Have medical conditions associated with bone loss Experience rapid weight loss that concerns you Have limited mobility or are unable to perform weight-bearing exercise Your GP can assess your individual fracture risk and determine whether investigations such as DXA scanning are appropriate
Addition of incretin therapy to metformin in type 2 diabetes
Qiao G, Lv T, Zhang M, Chen P, Sun Q, Zhang J, et al
