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In addition, choline, myristoleic acid, cuminaldehyde, 4-deoxypyridoxine, 10-(2,3-dihydroxypropoxy)-10-oxodecanoic acid, Val Pro Gln, linalool oxide (cis-pyran) and galactosylhydroxylysine were reduced in RA production and normalized after ASP-2pb intervention, and these eight metabolites were negatively correlated with RA symptoms such as posterior claw volume and plasma inflammatory cytokines including IL-1, TNF-, and IL-6, and are thought to be the key to the alleviation of RA by ASP-2pb intervention metabolites (23)

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