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The process from initial assessment to prescription often takes just a few days, though timelines vary
Current Pharmaceutical Design , 26(25), 2929-2961
doi: 10.3275/7745 62 ColacurciNMontiMGFornaroFIzzoGIzzoPTrottaCet al
However, it's important to note that NICE guidance (NG193) does not recommend opioids for chronic primary pain due to limited evidence of benefit and risks of dependence
These symptoms typically occur during the initial weeks of treatment or following dose increases, and often diminish over time as the body adjusts to the medication
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