retatrutide triple agonist glp-1 gip glucagon phase 2 obesity trial nejm 2023 Medscape Planned or ongoing phase 2

PMID: 7729267

Evidence Gaps: Most positive findings come from topical formulations or small studies

Additionally, GHK-Cu provides benefits minoxidil doesn't: stem cell activation, anti-inflammatory effects, antioxidant protection, and collagen stimulation

Many biologically active compounds whose benefits have been observed in clinical trials/animal studies might or might not exert antioxidant effects

However, many companies rely on external partners for downstream steps, in which case the shift to an oral format is less about capital investments and more about simplifying their CMO networka move which could lower both costs and operational risks