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Although first-generation basal analogues and NPH insulin are frequently administered once daily, greater flexibility and better coverage of basal insulin needs may be achieved by administering them twice daily
Safety protocols include regular ECGs and blood pressure checks to ensure the medication remains safe for the patient
doi: 10.1590/abd1806-4841.20153192 PMID: 25830991 Orfanos CE, (1983) Evidence for anti-inflammatory activities of oral synthetic retinoids: experimental findings and clinical experience. Br J Dermatol
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