BFRs are also of concern due to their widespread occurrence in the environment and adverse effects on living organisms, including humans
We may produce less ALDH, meaning acetaldehyde stays in the body for longer
Long before microaneurysms, dot-blot hemorrhages, or hard exudates become visible on fundus photographs or ophthalmoscopy, the retina has already sustained measurable neuronal and synaptic loss, reactive gliosis, impaired neurovascular coupling, and subtle but objective deficits in contrast sensitivity, color discrimination, dark adaptation, and electrophysiological responses
GPX4, ferroptosis, and diseases
It provides the highest bioavailability by bypassing digestion entirely