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Lei S, Clydesdale L, Dai A, Cai X, Feng Y, Yang D, et al
Research has demonstrated that GLP-1RAs significantly inhibit the expression of MMP-2 and MMP-9 in the human ovarian cancer cell line SKOV-3 within a TNF--induced inflammatory microenvironment, while simultaneously upregulating the levels of their inhibitors, tissue inhibitors-1 (TIMP-1) and tissue inhibitors-2 (TIMP-2) [78, 87]
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In clinical trials, some GLP-1 medications have helped patients lose 1520% of their body weight, making them a significant advancement in weight management
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