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GLP-1s have been rigorously studied since the Food and Drug Administration mandated safety trials in 2008
Mar-Apr 1997;27(2):135-41
Thus, in our experiments in a murine model of kidney fibrosis, TMAO or choline diet supplementation resulted in hyperactivation of ERK1/2, mTORC1 and SMAD3 pro-fibrotic signaling 46,50 (Supplementary Fig
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