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Mitochondria are involved in a series of biochemical events in cells, ordinarily, normal neurons have an intense energetic demand to support localized neuronal activities

But biological plausibility does not replace human clinical trial proof

Following PPI testing at 4 wks post-noise exposure, 36 of the 38 rats that tested positive for chronic NIT were randomly assigned to either the NHPN-1010 treatment group or the vehicle (saline) group, each with n = 18 cases, where two animals were excluded from the treatment phase due to health-related concerns

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So instead he landed up working on the proglucagon gene