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Golding points out that unless the enterohepatic circulation is disrupted, holotranscobalamin levels wont significantly decrease until the livers B12 stores are depleted (Golding, 2016)
Patients should be educated about the importance of maintaining treatment adherence, as discontinuation leads to recurrent deficiency within months to years
GLP-1 usually needs commitment
Therapeutic response to cyanocobalamin may decrease due to elderly age, infection, renal insufficiency, diabetes mellitus, marrow suppressants use (e.g
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