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Global prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in the overweight and obese population: a systematic review and meta-analysis

In this Ground Truths post Ill review them by 2 categories: (1) the peptides that have been FDA approved but are getting extensive off-label use

This may manifest as reduced enjoyment of previously favoured foods or, in some cases, mild nausea when consuming rich meals

Mazdutide, targeting GLP-1 and glucagon (but not GIP), reaches about 14-20% weight loss depending on dose and trial duration

Employers are weighing the cost of these medications against the long-term costs of obesity