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The NHS treatment pathway and the 2024 NICE guideline both assume B12 injections are given in a clinical setting against a confirmed deficiency, not self-sourced and self-administered

In addition to the conditions mentioned above, several risk factors increase the likelihood of B12 deficiency: Smoking Alcohol abuse Endocrine-related autoimmune disorders (such as diabetes or thyroid disorders) Gastrointestinal disorders like Crohns disease History of gastric bypass surgery or other stomach-altering surgeries Optimize Your Health

Most people choose a small gauge needle such as 27 and a 1/2 needle with a 1-2ml syringe

I believe many patients will choose physician-supervised care over purchasing products online. However, multiple panelists pointed out that there is no evidence or research that suggests that the reclassification of these drugs would limit the gray market

Disclose Medications: Let your provider know about any medications you are taking, especially those for acid reflux or diabetes (like Metformin), as these can interfere with B12 levels