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GutBrain Axis 101: Serotonin, 5HTP & Digestive Signaling Why 90 % of Serotonin Lives in Your Gut GLP-1s affect more than your gut

The standard FDA-approved escalation follows this timeline: Weeks 1-4: 2.5 mg weekly ( unit conversion for 2.5 mg ) Weeks 5-8: 5 mg weekly ( unit conversion for 5 mg ) Weeks 9-12: 7.5 mg weekly ( unit conversion for 7.5 mg ) Weeks 13-16: 10 mg weekly ( unit conversion for 10 mg ) Weeks 17-20: 12.5 mg weekly Week 20+: 15 mg weekly (you are here) That is a minimum of 20 weeks, nearly five months, before reaching the maximum dose

Patients using peptide therapy often benefit from ongoing monitoring to track fat loss, energy levels, and hormonal responses over time

There is also some extent to which weight loss happens in the brain, especially when it comes to GLP-1 agonists and GIP agonists, as mentioned in footnote 1

Patients were randomized to basal-bolus treatment with TOUJEO or LANTUS and treated for 26 weeks