The primary outcome of this study was the first diagnosis of CRC within 15 years from the initial treatment of GLP-1RAs or non-GLP-1RA diabetes medications (insulin, metformin, alpha-glucosidase inhibitors, dipeptidyl-peptidase-4 inhibitors (DPP-4i), sodium-glucose cotransporter-2 inhibitors (SGLT2i), sulfonylureas (SU), and thiazolidinediones (TZD))
Therefore, adolescents with obesity may be at a higher risk of ID because of unbalanced meals, which are high in calories but low in iron, whether absolute or relative to body mass, together with increased iron needs
It mimics the GLP-1 hormone, increasing satiety, slowing digestion, and reducing calorie intake
This investigational product targets the GLP-1 receptor and glucose-dependent insulinotropic polypeptide receptor (GIPR)
Clinical evidence shows most patients achieve meaningful weight loss at doses between 1.0 and 2.4 milligrams weekly, though individual response varies significantly