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10.1016/j.vph.2018.02.010 147 VukojevicJ.VrdoljakB.MalekinusicD.SiroglavicM.MilavicM.KolencD.et al (2020)

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Overall, most of those papers are in favor of a possible contribution of polymorphisms in folate-related genes as maternal risk factors for the birth of a child with DS, however, they are often conflicting and limited by the small sample size of case-control cohorts (Table 1)

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