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However, the side effects of long-term use of metformin in the patients with PCOS should not be ignored, which include gastrointestinal reactions, neurological adverse reactions, hypoglycemia, metabolic problems, and so on
Prevention of muscle atrophy
Additionally, metformin inhibits mitochondrial respiratory chain complex I, which lowers proton leak and ROS generation in hepatocyte mitochondria, thereby reducing hepatocyte apoptosis to treat DILI (99)
Why: Degradation may not be visible
All treatments were continued for 5 days
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