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The new study extends this concept to skin inflammation and proposes that increased FABP5 expression funnels these redox-active lipids toward cellular membranes while suppressing the expression of GPX4, the lipid peroxidationdetoxifying enzyme and key ferroptosis suppressor, thereby amplifying lipid peroxidation and promoting inflammatory cell recruitment (Fig
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P-PINP (procollagen type I N-terminal propeptide), a marker of bone formation, did not show a compensatory increase
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Most common side effect, typically resolves within minutes to hours
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