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Clinical considerations: Therapy should be carefully monitored due to dose sensitivity and potential androgenic effects

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adult population (BMI of 30 or higher) peaked around 2017-2020 (and may be declining slowly),[2] rates of severe obesity (BMI or 40 or higher) continue to climb steadily (currently around 10%)

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Visceral fatthe metabolically active adipose tissue surrounding internal organsposes greater health risks than subcutaneous fat, driving insulin resistance, cardiovascular disease, and metabolic dysfunction