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In addition, interventions targeting lactylation-associated enzymes, such as the p300 inhibitor C646, might be emerging as promising therapeutic strategies for regulating lactylation (Table 3)

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However, differences in sociodemographic profile and comorbidities were present, such as higher incomes and educational level of GLP-1 RAs users compared with SGLT-2 inhibitor users and DPP-4 inhibitor users suggesting selection bias in prescription