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Photoprotective and Antioxidant Signaling Consistent with MC1R engagement, MT-2 has been shown in in-vitro models to reduce UV-induced cyclobutane pyrimidine dimer (CPD) formation and attenuate reactive oxygen species (ROS) accumulation in melanocytes, paralleling the photoprotective signaling profile documented for MT-1 (Abdel-Malek et al., Cancer Research, 2005)
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These results, obtained from freshly patient samples, suggested the potential for achieving a clinical response in AML patients with high TLR2 expression using TLR2 pep-orid-liposome
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