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M.AtakisiE.CitilM.KaniciA.MerhanO.et al (2010)

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Ouellet-Morin, I

In chronically stimulated T-cells ( e.g ., in the tumor or persistent antigen context), researchers found a progressive loss of PGC-1 and other metabolic regulators, resulting in small, fragmented, and dysfunctional mitochondria in exhausted T-cells (68)