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The molecule can be described as a modified dipeptide analogue featuring multiple stereocenters and flexible aliphatic segments
This D-retro-inverso configuration preserves the three-dimensional side-chain topology of the original FOXO4 sequence maintaining functional mimicry of the FOXO4 forkhead domains interaction surface with p53 while conferring exceptional proteolytic stability compared to the native L-amino acid sequence
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(More information) The Dietary Guidelines for Americans recommend for adults to consume 1-2 cup-equivalents of dark-green vegetables per week, including cruciferous vegetables, as part of healthy meals
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