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Since gastrointestinal adverse effects are rarely severe and tend to diminish over time, they would therefore not be expected to cause a barrier to initiating and continuing treatment for most patients

The delayed gastric emptying effect often attenuates over time with long-acting GLP-1 agonists through tachyphylaxis, though the weight loss and glycemic benefits typically persist

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The results can last for several months, but maintenance treatments are often recommended to prolong the effects

It is composed of three amino acids: glycine, glutamine and cysteine