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Most GLP-1R agonists have gastrointestinal side effects, including nausea, vomiting, diarrhea and constipation, which may be more pronounced in elderly patients with AD and affect treatment compliance

In general, microglial retained more ramified processes following injury when inhibited with P2Y12, P2Y6, or P2X4 antagonists compared to P2X7

This is a stimulant laxative, which can cause cramping

This frequency applies to semaglutide, tirzepatide, and other common compounds