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AMPK Activation Acts as a metabolic regulator: turns on AMPK, the master energy sensor controlling glucose and fatty-acid oxidation

The low molecular weight peptides (~10 kDa) can cross the blood-brain barrier, theoretically delivering neurotrophic support directly to neurons

Given the harmful effects of eryptotic RBCs on endothelial cells and platelets, which can cause vascular inflammation and blood coagulation, these studies provide a rationale that links cigarette smoke to vaso-occlusive complications and atherogenesis

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