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Citation47 This may be due to the increase in ions (positive and negative) available in solution to interact with charged groups on the protein molecule and shield the charged amino acid residues from interacting

Seek medical advice if you experience: New or worsening vision problems Severe or progressive weakness Loss of coordination or balance Confusion or cognitive changes Seizures These symptoms could indicate underlying conditions requiring investigation

It is listed as a rare adverse reaction in UK product information for both oral and injectable B12 preparations, and most people tolerate B12 supplements well even at high doses

Researchers and laboratory professionals must follow all applicable institutional, local, state, and federal regulations governing the handling of research compounds