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Conclusions Ultimately, while further investigation will help clarify the risks and benefits of GLP-1 RAs with respect to diabetic retinopathy and vision-threatening complications, its clear that GLP-1 RAs confer proven mortality and cardiovascular benefit

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Amylins physiological roles include inhibition of glucagon secretion, reduction in food intake, delay in gastric emptying, activation of brown adipose tissue via the sympathetic nervous system, and increased energy expenditure, ultimately leading to decreased blood glucose levels and weight loss [95]