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It's a risk, and like any risk in a research setting, it's one that must be understood, monitored, and mitigated
HPLC/mass spectrometry quantification of 8-oxo-dG DNA was extracted from brain tissues using standard phenol chloroform methodology for which the methodological details have been published previously
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Towsen designs the protocol around your specific concern
Apply light pressure with clean gauze if needed, but do not rub the area
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