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These are complementary strategies that address weight through different biological pathways -- CagriSema through dual appetite suppression mechanisms, retatrutide through appetite suppression plus increased energy expenditure

C.KuverR.et al (2019)

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There is also some risk for unmeasured confounding, and factors like bias because of unmeasured variables, dosing differences, using brand as a proxy for target dose, and missing information could have affected the results