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Table II EMPA-REG OUTCOME trial: BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients
The identification of subgroups that are most likely to benefit from GLP-1RAs could be guided by biomarkers, and cardiac imaging may help determine whether the advantages of GLP-1RAs extend beyond the metabolic or obesity phenotypes
GhorbaniZToghaMRafieePAhmadiZSRasekh MaghamRDjalaliMet al
Memory (escape latency in the Morris water maze test), neurotransmitters (acetylcholine, dopamine, gamma-amino butyric acid (GABA)), and neurochemicals (BDNF, catalase, glutathione, Amyloid Beta and cyclic GMP) were analyzed from whole brain samples in young (8-weeks-old) and aged (16-months-old) rats following 12 days of supplementation (100 mg/d HED of 1-MX [UPLEVEL, Ingenious Ingredients L.P., Lewisville, TX, USA]) via oral gavage
PX, J-IM, and NN performed experiments
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