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Lixisenatide: ELIXA 26,38 This trial was different from the remainder of the CVOTs discussed in this review in that only ELIXA enrolled people with a recent acute coronary syndrome

Call me if: You're vomiting and can't keep water down You have severe pain at the injection site You see signs of infection (warmth, pus, spreading redness) You're having trouble breathing or showing signs of an allergic reaction You're so nauseous you can't eat for more than 24 hours You just feel really off, and something doesn't seem right Don't call me if: You have mild nausea (totally normal) You saw a drop of blood (also normal) You're tired on the first day (expected) You have a small bruise (happens sometimes) When in doubt, send a message through the patient portal or call

If you have a vitamin B12 deficiency, you may feel tired all the time due to B12 deficiency anemia

The primary concern is the potential for deterioration in blood glucose control, which can lead to hyperglycaemia

After a median follow-up of 104 weeks, treatment with tirzepatide was associated with a significant reduction in the risk of adjudicated death from cardiovascular causes or a worsening heart failure event (hazard ratio (HR) = 0.62