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Youle M, et al

GLP-1 agonists are medicines that work like the GLP-1 hormone produced in your body, helping to regulate blood sugar levels in several ways, including: Slowing digestion after a meal (some of these medications more than others) Reducing glucagon from the pancreas (which signals your cells to release stored glucose and increase blood glucose levels) Increasing insulin release from the pancreas Promoting the feeling of being full after eating These medicines help people with type 2 diabetes manage their blood sugar levels

Taking phentermine and topiramate together may be more effective for weight loss than taking each drug on its own

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They also release a hormone that slows down digestion and keeps food in a patient's stomach longer