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Commit to completing at least one full 4-week cycle before evaluating efficacy

But heres the critical factor that often gets missed: Regularly rotating injection sites

22,23 Since IGF-1R governs PI3K/AKT and Ras/ERK signaling pathways, 1 we next to test whether induction of p70S6K1 phosphorylation is dependent on K-Ras or PIK3CA mutation

Future opportunities include hybrid nanoplatforms that integrate redox responsiveness with imaging and enhanced safety, as well as the use of patient-specific GSH/GSSG profiles to guide individualized therapy