Slower transit times may contribute to increased fermentation of food by gut bacteria, producing additional gas
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Safe alternatives include metformin, SGLT2 inhibitors (empagliflozin, dapagliflozin), DPP-4 inhibitors (sitagliptin, linagliptin), and exenatide immediate-release or lixisenatide, which do not carry thyroid cancer warnings
thus liraglutide and oral semaglutide significantly reduced cardiovascular death, subcutaneous semaglutide and dulaglutide significantly reduced nonfatal stroke, albiglutide reduced the risk of nonfatal myocardial infarction, and epfeglenatide reduced the incidence of heart failure, while weekly exenatide or lixisenatide showed no significant benefit on any component of MACE