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In vitro studies have utilized human umbilical vein endothelial cells (HUVECs) to investigate angiogenic activity, human fibroblast cultures for wound migration assays, and tendon fibroblast primary cultures to examine collagen synthesis rates
If a patient is dealing with a B12 deficiency that is related to their diet, its possible they will not need further treatments, provided they make dietary changes, or they may only need injections annually or biannually
PubMed Link Stojanovic A, et al
Moreover, none of the available treatment options adequately restore tunical architecture or address the early molecular mechanisms that drive fibrosis [5]
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