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Graphical abstract Similar content being viewed by others Background Nephropathic cystinosis is a rare, autosomal recessive lysosomal storage disease with an incidence of 1:100,000 to 1:200,000 live births [1]

While the simulations are confined by these assumptions, it is worth noting that redox cycling is governed by thermodynamics, which according to the reduction potential of doxorubicin, are favourable with respect to the formation of superoxide should a semiquinone radical species be present 3

We identified the top 20 up- and downregulated genes in fibroblasts from semaglutide-treated hearts, confirming the consistency of these changes across different fibroblast subclusters

Syringe dead space: Standard syringes leave a small amount of solution in the needle hub after each injection

Even serious and difficult-to-treat diseases can yield meaningful benefit from this approach