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ROS subsequently activate RhoA/ROCK pathways to enhance vasoconstrictor sensitivity and oxidatively inactivate protein tyrosine phosphatases [327], prolonging phosphorylation of growth factor receptors
Considering the fact that Baf-A1 suppresses fusion of autophagosomes with the lysosomes 39 , our finding that DFO protected against ferroptosis suggests that lysosomal iron pool is involved in GSH depletion-induced cell death 48
Abbreviations AS: alpha synuclein DA: dopamine DAB: 3-diaminobenzidine hydrochloride GPX: glutathione peroxidase GPX1: glutathione peroxidase 1 GPX4: glutathione peroxidase 4 (phospholipid hydroperoxidase) HAAS: Honolulu-Asia Aging Study PD: Parkinson's disease PMI: post-mortem interval Se: selenium SN: substantia nigra TH: tyrosine hydroxylase
Legumes Legumes, such as beans and lentils, are a low glycemic index (GI) food, which means they are digested and absorbed slowly and are less likely to raise blood sugar levels
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