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Tissue permeability After subcutaneous injection, AOD 9604 spreads to adipose tissue through local capillaries and avoids systemic distribution

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Following PCR, the reactions were incubated with 1 l (20 U) of Anza TM 10 DpnI (Invitrogen) for 1 h to selectively digest the methylated parent plasmids, and the resulting PCR products were purified with GenElute PCR Clean-Up Kit (Sigma-Aldrich)

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Rapid correction of severe deficiency can occasionally cause hypokalaemia as haematopoiesis resumes, and potassium levels should be monitored in such cases