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Severe nausea, vomiting, and diarrhea can cause dangerous dehydration, and overdosing can trigger complications like pancreatitis or gallbladder problems
[9] [10] For patients with established cardiovascular disease, SGLT2 inhibitors are generally prioritised for cardiorenal protection, with GLP-1 receptor agonists with proven cardiovascular benefit considered when SGLT2 inhibitors are unsuitable
Murali S, Smith ER, Tiong MK, Tan SJ, Toussaint ND
Several innovative strategies should be prioritized to overcome these obstacles
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