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The department said it expects to make regulatory decisions on more of the eight pending submissions in the coming weeks and months

Ultimately, this means that berberine's effects as an insulin secretagogue will be diminished on lower-carbohydrate diets (although the GLP-1 mechanism is still in play)

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Over time, it can become an integral part of a comprehensive health plan that may include diet modification , regular physical activity , and monitoring of blood glucose levels