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This depends entirely on the treatment goal and formulation

A Root Cause Medicine Approach: A Comprehensive Guide On How To Test For Low Nitric Oxide Levels

Avoid taking high-dose B6 supplements without consulting your doctor: While the daily upper limit is set at 100 mg pyridoxine, there have been reported cases of pyridoxine-induced neuropathy in people taking 25 to 50 mg per day for longer than six months

So the better question is not "copper peptides vs retinol, which wins?" The better question is: What does your skin need right now

Your dose might change based on lab tests, how youre feeling, and other factors