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Thus, the clinical benefits for the risk of heart failure and kidney outcomes, except albuminuria, are likely to be a strength of SGLT2is, whereas those for the risk of stroke are a strength of GLP-1RAs (Graphical Abstract)
Follow-Up Visits and Outcomes Three-Month Check Weight: Down 3 kg (BMI 34 kg/m) HbA1c: Decreased to 7.8% from 8.6% Blood Pressure: Controlled at 128/80 mmHg Side Effects: Mild nausea during the first few weeks, which subsided with slow dose titration Six-Month Check Weight: Down a total of 6 kg (BMI 33 kg/m) HbA1c: Further improvement to 7.3% Cardiometabolic Indicators: Mild improvement in LDL cholesterol (from 110 mg/dL to 98 mg/dL)
It typically improves after the first few weeks at each new dose but can persist in some people
The MHRA, as the UK's medicines regulator, requires that all IMPs are stored in accordance with the conditions specified in the IMPD and the IMP label
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