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Funding This work was supported by Guizhou Provincial Science and Technology Projects (2018-1102)
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Digestive Discomfort: Ozempic is known to produce gastrointestinal side effects such as nausea, vomiting, and diarrhea, especially during the initial weeks of treatment
The best-fit patients for GLP-1 RAs are those with ASCVD with a high risk of future stroke (e.g., with history of stroke or revascularization, or with evidence of significant artery narrowing)
IGF-1 LR3's structural modifications allow it to remain unbound and biologically active for 2030 hours post-injection, delivering sustained systemic exposure to IGF-1 receptor signaling
